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Diabetes

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Female doctor talking with patient along coworker in ICU. Man is lying on bed amidst essential workers. Healthcare workers are in protective workwear.

The antimalaria drug hydroxychloroquine has generated significant controversy. A new study suggests that if it is given early, it can reduce mortality in people with severe COVID-19. But our expert points out weaknesses in the study’s design.

Amid an ongoing search for an effective COVID-19 treatment, the debate about the antimalaria drug hydroxychloroquine (HCQ) continues.

There was plenty of hype about the drug during the early months of the pandemic. On March 28, 2020, the Food and Drug Administration (FDA) granted Emergency Use Authorization (EUA), allowing doctors to use HCQ and chloroquine (CQ) products in situations where clinical trials were not an option.

Last month, the FDA withdrew the EUA. The agency explains that it “has determined that CQ and HCQ are unlikely to be effective in treating COVID-19 for the authorized uses in the EUA. Additionally, in light of ongoing serious cardiac adverse events and other serious side effects, the known and potential benefits of CQ and HCQ no longer outweigh the known and potential risks for the authorized use.”

Clinical trials using the drug have shown mixed results and been marred with controversy. After an investigation by The Guardian into the quality of data analysis provided by a company called Surgisphere, the authors of one high-profile study in The Lancet retracted the paper.

Several institutions have since halted their HCQ studies, including the World Health Organization (WHO) and the National Institutes of Health (NIH).

Now, a new study in the International Journal of Infectious Diseases — by researchers from the Henry Ford Health System, in Michigan — reports that treatment with HCQ alone and in combination with the antibiotic azithromycin reduced the number of deaths among people in the hospital with severe COVID-19.

Comparing mortality rates

The corresponding author is Dr. Marcus J. Zervos, an infectious disease specialist at Henry Ford Hospital and the Wayne State University School of Medicine, both in Detroit, MI.

For their study, the team retrospectively reviewed the medical records of 2,541 individuals who received treatment for COVID-19 in Henry Ford Health System hospitals.

The aim of the research was to compare how many people with COVID-19 died while in the hospital after receiving either HCQ, HCQ and azithromycin, azithromycin on its own, or “other treatments for COVID-19,” as the authors explain in their paper.

Treatment with HCQ, azithromycin, or both began within 24 hours of hospital admission in 82% of cases, and within 48 hours of admission in 91% of cases.

Among the 2,541 patients in the study, 460 died, which equates to an overall mortality rate of 18.1%. In the group of 409 patients who received neither HCQ nor azithromycin, 108 died, representing a mortality rate of 26.4%.

A total of 1,202 patients received only HCQ, of whom 162 died, a mortality rate of 13.5%, while out of the 147 patients who received only azithromycin, 33 died, equating to a mortality rate of 22.4%.

Among the 783 patients who received a combination treatment of HCQ and azithromycin, 157 patients died. This reflects a mortality rate of 20.1%.

While these results sound encouraging, Dr. Hanh Le, who is the senior director of medical affairs at Healthline Media, shared her concerns about the study with Medical News Today.

“As an observational study, it would have been good to have insights into what factored into the treatments that the patients received. For example, of the patients who received neither drug, why were most of them 65 or older?” Dr. Le pointed out. “Unfortunately, the study authors did not address that.”

Study limitations

Dr. Le explained that the average age of those who received neither HCQ nor azithromycin was significantly higher than those who received HCQ.

Specifically, the average age in the group who received other COVID-19 treatments was 68.1 years, the median age was 71 years, and 64.1% were over the age of 65. In the HCQ group, on the other hand, the average age was 63.2 years, the mean age was 53 years, and 48.9% were over 65.

Patients in the HCQ group were also significantly more likely to receive steroids in addition to the drug. While 78.9% of patients in this group received steroids, only 35.7% of patients in the other COVID-19 treatment groups did.

“In addition, white race is a risk factor they identified, and it too was unbalanced,” Dr. Le added.

In the group receiving other COVID-19 treatments, 45.5% were white, while in the HCQ group, 27.6% were white.

“We attribute our findings that differ from other studies to early treatment, and part of a combination of interventions that were done in supportive care of patients, including careful cardiac monitoring,” Dr. Zervos comments in a press release.

“Our dosing also differed from other studies not showing a benefit of the drug. And other studies are either not peer-reviewed, have limited numbers of patients, different patient populations, or other differences from our patients,” he continued.

The study authors do urge caution in light of their findings:

“Our results should be interpreted with some caution and should not be applied to patients treated outside of hospital settings,” they write in the paper. “Our results also require further confirmation in prospective, randomized controlled trials that rigorously evaluate the safety, and efficacy of [HCQ] therapy for COVID-19 in hospitalized patients.”

Nowadays, Nigerians who lead sedentary lifestyles and who have adopted irregular food habits, appear to be more prone to liver diseases than others. Fatty liver disease is the result of a build-up of fat in the liver. If the liver is healthy, there should be little or no fat in it. However, sometimes, fat molecules begin to collect in the liver cells. Small amounts of fat in the liver usually cause no problems. However, when too much fat builds in this organ, it can pose a lot of health hazards.

With the exception of the brain, the liver is the most complex organ and second largest organ in the body. Its function is to process everything we eat or drink and filter harmful substances from the blood. This process is however interrupted when the liver contains too much fat. When fat accounts for more than five percent of the liver’s weight, the condition is described as fatty liver.

It is becoming one of the most common types of liver disease and it’s also one of the causes of liver cancer and cirrhosis. The disease may also occur due to metabolic problems such as diabetes, obesity or Hepatitis B and C infection.

A diagnosis of fatty liver could raise the alarm for an impending Type 2 diabetes. Fatty liver disease can lead to an inflamed liver and scarring. This is called alcoholic hepatitis if it’s caused by drinking too much alcohol and non-alcoholic steatohepatitis if it’s not related to alcohol.

Risk factors

From what I have explained so far, it should be obvious that fatty liver disease is a lifestyle disease. Most people living with this disease are fat, obese and they take alcohol.

It is more common in men and persons above the age of 50. Hypertensive and diabetic patients are most likely to be diagnosed with fatty liver as they are already battling with high blood sugar, glucose and cholesterol.

However, chemicals like methotrexate and tamoxifen can, but rarely cause non-alcoholic fatty liver.

Symptoms

Non-alcoholic fatty liver disease usually causes no signs and symptoms. When it does, they may include fatigue, poor appetite, pain in the upper right abdomen and weight loss.

Its complications include a swollen abdomen, itchy skin, vomiting of blood,  confusion or poor memory, weakness and muscle wasting and jaundice.

Diagnosis

Fatty liver disease can sometimes be difficult to diagnose because one may not have any symptoms. There is no single test that can be used to diagnose fatty liver disease, but one may carry out some blood tests, liver biopsy,  ultrasound, CT or MRI scan which help to create images of the liver. These images will show if there are any forms of fat in the liver.

Prevention

You may be able to prevent non-alcoholic fatty liver disease by maintaining a healthy weight for your height. Being active try to do at least 150 minutes of moderate exercise each week or 30 minutes of exercise for days.

Those who are obese or overweight, a gradual weight loss and regular exercise is advised. This not only helps with fatty liver but also it will help to reduce other risks of developing cardiovascular problems.

Limit or avoid alcoholic beverages because alcohol even in modest amounts may make fatty liver worse.

Eating healthy foods that are low in saturated fat and reduce your sugar intake to control your blood sugar. Manage your cholesterol levels and use liver supplements.

Conclusion

Alcoholic fatty liver disease is reversible. The liver should return to normal if one stops drinking alcohol. Even if one has been a heavy drinker for many years, reducing or stopping alcohol intake will have important short and long-term benefits on the liver and one’s overall health.

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With the vast majority of people surrounded by computers and the internet, either at home or work, sometimes tracking your life can be more convenient when it’s done online. Whether you’re calorie counting, tracking your weight or devising a new exercise plan, there are a number of free online tools that can help you to achieve success. If you’re considering starting a new exercise regime or eating plan, be sure to check out these great online tools for some handy hints and great tracking techniques.

Online Tools For Tracking Your Health

Calorie Burn Calculator

The Calorie Burn Calculator can help you to determine how many calories your everyday activities will burn. You may be surprised but simply daily tasks, such as brushing your teeth and carrying an infant, all burn calories. While the Calorie Burn Calculator helps to track your everyday life, you can also add just about any activity, including the difficulty level and duration of the exercise. If you’re an avid cyclist, for instance, you can enter cycling for leisure, fast-paced riding, and even mountain biking, to determine how many calories you have burned.

If you haven’t yet discovered the benefits of cycling, it’s time to see what all the fuss is about. With various mountain bikes for sale, you can easily find a style that suits your skill level and your budget. One of the best things about cycling is that you can ride in just about any environment. Get the most out of your exercise routine and bring the fun back to your weekends, by leisure cycling along pristine coastlines or breathtaking mountain ranges.

Diet & Weight Loss Trackers

What seems like a limitless number of diet and weight loss trackers are now available on the internet. When beginning a new health kick, most people will record their starting weight to enable them to keep track of their progress. A diet and weight loss journal or tracker is a great way to regulate your eating and exercise habits. Tracking what you eat will enable you to see what foods make you gain weight and which foods help you to lose weight. An activity log can also help by allowing you to record your daily or weekly exercise routine.

While it’s sometimes easy to slip away from your dieting plan and enjoy an unhealthy snack or two, recording your results often helps people to be more honest with themselves, about what they are actually consuming. Understanding why you are gaining weight or developing an unhealthy lifestyle is the first step in changing your future.

Free online tools are a great way to gain extra motivation and encouragement for your diet plan. If you’ve tried dieting in the past but have failed miserably (haven’t we all!) then why not enlist the help of professionally designed programs online?

An Abuja based herbal doctor, Dr Bamidele Joshua, said the consumption of mango leaves helps in the treatment of kidney and gallstones among others.

He told the News Agency of Nigeria on Wednesday in Abuja that consumption of mango leaves also helps in the treatment of many health conditions.

According to him, Mango leaves contain vitamins C, A and B as well as vital minerals such as Copper, Potassium and Magnesium.

He explained that the leaves could be boiled to be taken as water or dried into powder form to be used in any food or drink.

Joshua added that for medicinal purposes, the use of young and tender leaves was best for optimal benefits.

The expert noted that the consumption of the leaves helps prevent and regulate diabetes, lowers blood pressure, fights restlessness and stops hiccups.

Mango leaves are very useful for managing diabetes. The tender leaves of the mango tree contain tannins called anthocyanidins that may help in treating early diabetes.

Soak the leaves in a cup of water overnight, strain and drink this water to help relieve the symptoms of diabetes. It also helps in treating hyperglycemia.

Mango leaves also help to lower blood pressure as they have hypotensive properties that help in strengthening the blood vessels and treat the problem of varicose veins.

People suffering from restlessness due to anxiety should add few mango leaves to their bathing water. This helps in relaxing and refreshing the body.

Daily intake of a finely grounded powder of mango leaves with water kept in a tumbler overnight helps in breaking kidney and gallbladder stones as well flush them out.

Put some mango leaves in warm water, close the container with a lid, and leave it overnight. Next morning filter the water and drink this concoction on an empty stomach.

Regular intake of this infusion flushes out toxins from the body and keeps the stomach clean,” he said.

He however enjoined patients with serious health challenge to seek medical advice before consumption.

The health benefits of watermelon include the prevention of kidney disorders, high blood pressure, the prevention of cancer, diabetes, heart disease, heat stroke, macular degeneration and impotence.

The question is, why is there so much craze for the watermelon? At first glance, it may seem like nothing more than a big ball of water.  We all know that there is nothing more refreshing than a big, chilled wedge of watermelon on a hot, summer day and it does sport a stylish scientific name of Citrullus Lanatus, but what’s the real reason so many people flock to grocery stores every summer to buy a big, awkward fruit like this one? Well, it is hard to narrow it down to a single reason; there are actually a lot of them.

What Is Watermelon?

Watermelons are considered a vine-like flowering plant that is actually native to Southern Africa, and it is there that the wild varieties are in the greatest abundance, ranging from super sweet to bitter, and varying in size as well. They moved north to Egypt, and were cultivated in the Nile River Valley, and eventually moved east into China, roughly 1,000 years ago. Now, watermelon is grown around the world, and in 44 of the 50 states in America. It is specifically selected to grow larger and juicier, resulting in the huge fruits that many of us are familiar with. The green outer rind is hard and fleshy, and rarely eaten, while the interior is soft, red or pink flesh containing the many seeds; this is the part of watermelon which is typically eaten.

As for accessing the total medicinal benefits of watermelons, it is highly dependent on the variety of watermelon and the ripeness. Beta-carotene and lycopene is usually bio-available in the highest quantities once the watermelon is completely ripe, and don’t be afraid to eat some of the watermelon rinds; there are quite a few nutrients in there as well, particularly the roughage and fiber.

Nutritional Value Of Watermelon

The long list of healthy or beneficial effects of watermelons are mainly derived from its unique nutrients, vitamins, minerals, and organic compounds. These include significant amounts of vitamin C, calcium, magnesium, fiber, protein, and a very large amount of potassium. Furthermore, they contain vitamin A, vitamin B6, niacin, thiamin, and a wide variety of carotenoids and phytonutrients, including lycopene!

These components of watermelons contribute to its major impact on health; let’s explore some more details of those benefits below.

Health Benefits Of Watermelon

Health benefits of watermelon include:

Treats Kidney Disorders

Watermelons contain a lot of potassium, which is very helpful in cleaning or washing out the toxic depositions in the kidney. Moreover, it is helpful in reducing the concentration of uric acid in the blood, thereby reducing the chances of kidney damage and the formation of renal calculi in that organ. In addition to this, being high in water content, it induces frequent urinating, which is again helpful for cleaning of the kidneys. Also, the antioxidants present in watermelon ensure good health of the kidneys for a long time and reduce signs of premature ageing like wrinkles and age spots on the skin.

Prevents Heat Stroke

Watermelon is effective in reducing both your body temperature and blood pressure. Many people in tropical regions eat this fruit every day in the afternoon during the summer to protect themselves from heat stroke. In India, you will find the fruit being sold by vendors on almost every street during the summer season. The high amount of water contained in watermelon also stimulates a release of excess liquid in the form of sweat, which cools your body further during hot summer days.

Regulates Blood Pressure

The good amount of potassium and magnesium that is present in watermelons is very beneficial in terms of bringing down blood pressure. Potassium is considered a vasodilator, meaning that it releases the tension of blood vessels and arteries, thereby stimulating increased blood flow and reducing the stress on the cardiovascular system. The carotenoids present in these fruits also prevent hardening of artery walls and veins, thereby helping to reduce blood pressure and the chances of blood clots, strokes, heart attacks, and atherosclerosis.

Prevents Cancer

Watermelons have been in the public eye more and more in recent years, primarily because of their impressive level of lycopene, a carotenoid phytonutrient compound that is increasingly being linked to cancer prevention. As the years go by and the studies continue to bring in consistent results, lycopene has been shown to significantly reduce the risks of prostate, breast, colon, lung, and endometrial cancer. All in all, between the antioxidant potential of vitamin C and the impact of lycopene, watermelon is a great anti-cancer fruit!

Controls Diabetes

Diabetic patients, who are supposed to have a low energy and low sugar diet, often complain about starving since they don’t get to eat their staple diets, which gives them the feeling of being half fed. Watermelons can be a good supplement for them. In spite of being sweet in taste, a thick wedge will give you very few calories, since ninety-nine percent of its total weight is composed of water and roughage. Moreover, the various vitamins and minerals such as potassium and magnesium help in proper functioning of insulin in the body, thus lowering the blood sugar level. Arginine, another component found in watermelons, is very effective at enhancing the impact of insulin on blood sugar. Diabetic patients can also have curries, steaks, and salads made from watermelon rinds, which are even lower in sugar.

Heart Care

Lypocene, a carotenoid found in abundance in watermelon, improves cardiac functions. Beta-carotene, known for its remarkable antioxidant and anti-ageing properties, also keeps you young at heart and prevents age-related cardiac problems. The roughage in watermelon and its very low energy, along with help from vitamin-C, carotenoids and potassium (potassium cuts the risk of a heart attack), helps to reduce cholesterol and keep your heart safe from a variety of dangerous conditions.

Macular Degeneration

Don’t worry about eye health and macular degeneration if you eat plenty of watermelons, because, between the beta-carotene, vitamin-C, lutein, and zeaxanthin, your eyes are well protected. They will ensure the protection of your eyes from age-related blindness and degeneration, and these antioxidants will protect your eyes from other age-related ailments such as drying up of eyes and optical nerves, as well as glaucoma.

Cures Impotence

Arginine, present in watermelon, is beneficial in curing erectile dysfunction, and the stimulating nature of the chemical can boost libido, reduce frigidity and give a kick start to your love life after you enjoy a few slices of watermelon together!

Other Benefits: Lypocene is found to be effective in repairing damaged tissues. Watermelon seeds are rich in beneficial fats and proteins. Watermelons also contain phytonutrients which have very good effects on the health and proper functioning of internal organs, eyes, and the secretion system.

How you react to being diagnosed with Type 2 diabetes does not have to dictate how you feel about the disease. Type 2 diabetes, while a lethal disease, is not a death sentence. Your life is not at immediate risk just because you are a diabetic. Even though it is a serious cause for concern and you most definitely should work on a solution, there is no need to damn yourself or lose spirit.

It is certainly possible to live well despite having to control the type of carbohydrates and fats you need to eat each and every day. But there is hope even in doing a few but essential things to change your health.

It is all about blood sugar. Hyperglycemia is the condition underlying this form of diabetes and most of its problems…

  • cardiovascular conditions,
  • nerve and kidney damage,
  • skin problems, and
  • impaired vision

are all caused by chronically elevated blood sugar. For this reason, the first step to living well is to control your food intake so the high readings no longer cause internal damage. Talk to your doctor to determine the target range you should strive for. He can give you practical advice tailored for you so you can make daily progress.Keeping blood sugar readings within a reasonable range is your most important task: this is needed to ensure the disease does not exacerbate and add insult to injury.

Let’s talk about nutrition. Eating healthily is the key to living well with Type 2 diabetes. By eating healthy foods, you will gradually reduce your blood sugar. What and how you eat makes a difference. Your doctor can fill you in on more details. Do not overlook the importance of having a quality diet. Keep your blood sugar levels in line with delicious recipes and daily meal plans.

Next, comes exercise. Increase your daily activity and develop several blood sugar busting exercise routines. Exercise is essential for everyone, never mind people diagnosed with Type 2 diabetes. Without physical activity, our health is left vulnerable to unpredictable circumstances. Don’t invite illnesses upon yourself by being sedentary.

Type 2 diabetics can improve their condition with regular exercise. Learn to enjoy physical activity sooner rather than later, because it is one of the most important habits you can develop in your life.

Also, living well requires you maintain a healthy body weight. Work on dropping a few pounds if you are above the ideal range. Exercising and eating well are the two main ingredients for weight loss, so dedicate your efforts in these areas so your weight is no longer a problem.

Uncontrolled blood sugar levels will shave years off your life. Lower your blood sugar, lose weight, and stop Type 2 diabetes and its complications in their tracks. Provided you are consistent; it will just be a matter of time.

Although managing your disease can be very challenging, Type 2 diabetes is not a condition you must just live with. You can make simple changes to your daily routine and lower both your weight and your blood sugar levels. Hang in there, the longer you do it, the easier it gets.

In functional medicine, we believe that every system in the body is connected. Your digestive and hormonal systems, for example, aren’t independent of one another. At the center of it all is a properly functioning digestive system.

When your gut is unhealthy, it can cause more than just stomach pain, gas, bloating, or diarrhea. Because 60-80% of our immune system is located in our gut, gut imbalances have been linked to hormonal imbalances, autoimmune diseases, diabetes, chronic fatigue, fibromyalgia, anxiety, depression, eczema, rosacea, and other chronic health problems.

I believe the gut is the gateway to health, and the first step I take with all of my patients regardless of their diagnosis is to heal the gut. I use a system called The 4R Program, which is a simple approach to repairing your gut and restoring your body’s balance.

10 Signs You Have an Unhealthy Gut:

1. Digestive issues like bloating, gas, diarrhea

2. Food allergies or sensitivities

3. Anxiety

4. Depression

5. Mood swings, irritability

6. Skin problems like eczema, rosacea

8. Autoimmune disease

9. Frequent Infections

10. Poor memory and concentration, ADD or ADHD

The 4 R Program

1. Remove

Remove the bad. The goal is to get rid of things that negatively affect the environment of the gut, such as inflammatory foods, infections, and irritants like alcohol, caffeine, or drugs.

Inflammatory foods, such as gluten, dairy, corn, soy, eggs, and sugar, can lead to food sensitivities. I recommend an elimination diet as the starting point to identify which foods are problematic for you, in which you remove the foods for two weeks or more and then add them back in, one at a time, taking note of your body’s response.

Infections can be from parasites, yeast, or bacteria. A comprehensive stool analysis is key to determining the levels of good bacteria as well as any infections that may be present. Removing the infections may require treatment with herbs, anti-parasite medication, antifungal medication, antifungal supplements, or even antibiotics.

2. Replace

Replace the good. Add back in the essential ingredients for proper digestion and absorption that may have been depleted by diet, drugs (such as antacid medications) diseases or aging. This includes digestive enzymes, hydrochloric acid, and bile acids that are required for proper digestion.

3. Reinoculate

Restoring beneficial bacteria to reestablish a healthy balance of good bacteria is critical. This may be accomplished by taking a probiotic supplement that contains beneficial bacteria such as bifidobacteria and lactobacillus species. I recommend anywhere from 25 -100 billion units a day. Also, taking a prebiotic (food for the good bacteria) supplement or consuming foods high in soluble fiber is important.

4. Repair

Providing the nutrients necessary to help the gut repair itself is essential. One of my favourites supplements is L-glutamine, an amino acid that helps to rejuvenate the gut wall lining. Other key nutrients include zinc, omega-3 fish oils, vitamin A, C, and E, as well as herbs such as slippery elm and aloe vera.

No matter what your health issue is, the 4R program is sure to help you and your gut heal! I have witnessed dramatic reversal of chronic and inflammatory illnesses in a very short period of time by utilizing this simple approach.

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Researchers suggest that sodium – which we commonly ingest through salt, or sodium chloride – could increase the risk of type 2 diabetes and latent autoimmune diabetes in adults.

Diabetes is a common condition that affects more than 29 million people in the United States, according to the Centers for Disease Control and Prevention (CDC). Type 2 diabetes accounts for up to 95 percent of all diagnosed cases and is characterized by abnormal levels of blood sugar.

This type of diabetes is most often diagnosed in middle-aged and senior people. Another metabolic condition called latent autoimmune diabetes in adults (LADA) is often misdiagnosed as type 2 diabetes; it also appears later in adulthood.

LADA is a more slowly progressing disease, and it does not initially require insulin treatment.

A new study conducted by Dr Bahareh Rasouli, of the Institute of Environmental Medicine at the Karolinska Institutet in Stockholm, Sweden – in collaboration with researchers from other Swedish and Finnish institutions – now looks at the impact of sodium intake on the risk of type 2 diabetes and LADA.

The researchers have presented their findings at the annual meeting of the European Association for the Study of Diabetes, held in Lisbon, Portugal.

High sodium intake may be a risk factor

Existing research had already suggested that the sodium we usually absorb from our daily intake of salt may significantly increase the risk of developing type 2 diabetes.

The team explains that this may be because sodium impacts insulin resistance, but also because excess salt can lead to hypertension and gaining excess weight. But until now, no studies had looked at the impact of sodium intake on the risk of LADA.

Dr Rasouli and colleagues analyzed data from the Epidemiological Study of Risk Factors for LADA and Type 2 Diabetes, which is a large Swedish cohort study.

Questionnaires were used to collect information about the participants’ daily diets. These data then allowed the team to calculate the daily caloric, nutrient, and sodium intake for each participant.

Dr Rasouli and colleagues also took into consideration genetic risk factors for diabetes, and the participants were split into “high risk” and “other” categories depending on their genetic profile.

Confounding variables, including age, sex, body mass index (BMI), smoking, physical activity levels, and alcohol intake, were also adjusted for.

The researchers found that each extra gram of sodium (or 2.5 grams of salt) per day was linked to a 43 percent higher risk of type 2 diabetes. For LADA, each extra gram of sodium led to a 73 percent increase in developing the condition.

Participants were also divided into three groups depending on the quantity of their sodium intake. These were “low consumption” (for under 2.4 grams of sodium daily, or up to 6 grams of salt), “medium consumption” (2.4 to 3.15 grams of sodium, or up to 7.9 grams of salt), and “high consumption” (more than 3.15 grams of sodium daily, or more than 7.9 grams of salt).

It was noted that the people who fell within the high consumption category were at a 58 percent higher risk of developing type 2 diabetes than the individuals in the low consumption group.

People with a high genetic risk of diabetes who also had a high daily sodium intake were almost four times as likely to develop LADA than people with a low daily intake of sodium.

Based on these findings, the researchers “confirm an association between sodium intake and type 2 diabetes.” They add that “high sodium intake may be a risk factor for LADA, especially in carriers of high risk HLA [human leukocyte antigen] genotypes.” These are people who already carry a significant genetic risk of diabetes.

The authors suggest that their study may lead to fresh prevention strategies for diabetes, and especially LADA.

These findings may have important implications in the primary prevention of diabetes with adult onset.

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13 Proven Health Benefits of Coffee

It is loaded with antioxidants and beneficial nutrients that can improve your health.

The studies show that coffee drinkers have a much lower risk of several serious diseases.

Here are the top 13 evidence-based health benefits of coffee, that have been confirmed in actual human studies.

1. Coffee Can Improve Energy Levels and Make You Smarter

Coffee can help people feel less tired and increase energy levels (1, 2).

This is because it contains a stimulant called caffeine, which is actually the most commonly consumed psychoactive substance in the world (3).

After you drink coffee, the caffeine is absorbed into the bloodstream. From there, it travels into the brain (4).

In the brain, caffeine blocks an inhibitory neurotransmitter called Adenosine.

When that happens, the amount of other neurotransmitters like norepinephrine and dopamine actually increases, leading to enhanced firing of neurons (5, 6).

Many controlled trials in humans show that coffee improves various aspects of brain function. This includes memory, mood, vigilance, energy levels, reaction times and general cognitive function (7, 8, 9).
Bottom Line: Caffeine blocks an inhibitory neurotransmitter in the brain, which leads to a stimulant effect. This improves energy levels, mood and various aspects of brain function.

2. Coffee Can Help You Burn Fat

Did you know that caffeine is found in almost every commercial fat burning supplement?

There’s a good reason for that… caffeine is one of the very few natural substances that have actually been proven to aid fat burning.

Several studies show that caffeine can boost the metabolic rate by 3-11% (10, 11).

Other studies show that caffeine can specifically increase the burning of fat, by as much as 10% in obese individuals and 29% in lean people (12).

However, it is possible that these effects will diminish in long-term coffee drinkers.

Bottom Line: Several studies show that caffeine can increase fat burning in the body and boost the metabolic rate.

3. The Caffeine Can Drastically Improve Physical Performance

Caffeine stimulates the nervous system, causing it to send signals to the fat cells to break down body fat (13, 14).

But caffeine also increases Epinephrine (Adrenaline) levels in the blood (15, 16).

This is the “fight or flight” hormone, designed to make our bodies ready for intense physical exertion.

Caffeine makes the fat cells break down body fat, releasing them into the blood as free fatty acids and making them available as fuel (17, 18).

Given these effects, it is not surprising to see that caffeine can improve physical performance by 11-12%, on average (29, 20).

Because of this, it makes sense to have a strong cup of coffee about a half an hour before you head to the gym.

Bottom Line: Caffeine can increase adrenaline levels and release fatty acids from the fat tissues. It also leads to significant improvements in physical performance.

4. There Are Essential Nutrients in Coffee

Coffee is more than just black water. Many of the nutrients in the coffee beans do make it into the final drink.

A single cup of coffee contains (21):

Riboflavin (Vitamin B2): 11% of the RDA.
Pantothenic Acid (Vitamin B5): 6% of the RDA.
Manganese and Potassium: 3% of the RDA.
Magnesium and Niacin (B3): 2% of the RDA.
Although this may not seem like a big deal, most people are drinking more than one cup per day. If you drink 3-4, then these amounts quickly add up.

Bottom Line: Coffee contains several important nutrients, including Riboflavin, Pantothenic Acid, Manganese, Potassium, Magnesium and Niacin.

5. Coffee May Lower Your Risk of Type II Diabetes

Type 2 diabetes is a gigantic health problem, currently afflicting about 300 million people worldwide.

It is characterized by elevated blood sugars in the context of insulin resistance or an inability to secrete insulin.

For some reason, coffee drinkers have a significantly reduced risk of developing type 2 diabetes.

The studies show that people who drink the most coffee have a 23-50% lower risk of getting this disease, one study showing a reduction as high as 67% (22, 23, 24, 25, 26).

According to a massive review that looked at data from 18 studies with a total of 457,922 individuals, each daily cup of coffee was associated with a 7% reduced risk of developing type 2 diabetes (27).

Bottom Line: Several observational studies show that coffee drinkers have a much lower risk of getting type II diabetes, a serious disease that currently afflicts about 300 million people worldwide.

6. Coffee May Protect You From Alzheimer’s Disease and Dementia

Smiling Elderly Woman

Alzheimer’s disease is the most common neurodegenerative disease and the leading cause of dementia worldwide.

This disease usually affects people over 65 years of age.

Unfortunately, there is no known cure for Alzheimer’s.

However, there are several things you can do to prevent the disease from showing up in the first place.

This includes the usual suspects like eating healthy and exercising, but drinking coffee may be incredibly effective as well.

Several studies show that coffee drinkers have up to a 65% lower risk of getting Alzheimer’s disease (28, 29, 30).

Bottom Line: Coffee drinkers have a much lower risk of getting Alzheimer’s disease, which is a leading cause of dementia worldwide.

7. Caffeine May Lower The Risk of Parkinson’s

Parkinson’s disease is the second most common neurodegenerative disease, right after Alzheimer’s.

It is caused by death of dopamine-generating neurons in the brain.

Same as with Alzheimer’s, there is no known cure, which makes it that much more important to focus on prevention.

Coffee Beans Spread Horizontally, Smaller

In studies, coffee drinkers have a much lower risk of developing Parkinson’s disease, with a reduction in risk ranging from 32-60% (31, 32, 33, 34).

In this case, it appears to be the caffeine itself that is causing the effect. People who drink decaf don’t have a lower risk of Parkinson’s (35).

Bottom Line: Coffee drinkers have up to a 60% lower risk of getting Parkinson’s disease, the second most common neurodegenerative disorder.

8. Coffee Appears to Have Protective Effects on The Liver

The liver is an amazing organ that carries out hundreds of important functions in the body.

Several common diseases primarily affect the liver, including hepatitis, fatty liver disease and others.

Many of these diseases can lead to a condition called cirrhosis, in which the liver has been largely replaced by scar tissue.

It turns out that coffee may protect against cirrhosis. People who drink 4 or more cups per day have up to an 80% lower risk (36, 37, 38).

Bottom Line: Coffee drinkers have a much lower risk of developing cirrhosis, which can be caused by several diseases that affect the liver.

9. Coffee Can Fight Depression and Make You Happier

Depression is a serious mental disorder that causes a significantly reduced quality of life.

It is incredibly common and about 4.1% of people in the U.S. currently meet the criteria for clinical depression.

In a Harvard study published in 2011, women who drank 4 or more cups per day had a 20% lower risk of becoming depressed (39).

Another study with 208,424 individuals found that those who drank 4 or more cups per day were 53% less likely to commit suicide (40).

Bottom Line: Coffee appears to lower the risk of developing depression and may dramatically reduce the risk of suicide.

10. Coffee Drinkers Have a Lower Risk of Some Types of Cancer

Cancer is one of the world’s leading causes of death and is characterized by uncontrolled growth of cells in the body.

Coffee appears to be protective against two types of cancer… liver cancer and colorectal cancer.

Liver cancer is the third leading cause of cancer death in the world, while colorectal cancer ranks fourth (41).

Studies show that coffee drinkers have up to a 40% lower risk of liver cancer (42, 43).

One study of 489,706 individuals found that those who drank 4-5 cups of coffee per day had a 15% lower risk of colorectal cancer (44).

Bottom Line: Liver and colorectal cancer are the 3rd and 4th leading causes of cancer death worldwide. Coffee drinkers have a lower risk of both.

11. Coffee Does Not Cause Heart Disease and May Lower The Risk of Stroke

It is often claimed that caffeine can increase blood pressure.

This is true, but the effect is small (3-4 mm/Hg) and usually goes away if you drink coffee regularly (45, 46).

However, the effect may persist in some people, so keep that in mind if you have elevated blood pressure (47, 48).

That being said, the studies do NOT support the myth that coffee raises the risk of heart disease (49, 50).

In fact, there is some evidence that women who drink coffee have a reduced risk of heart disease (51).

Some studies also show that coffee drinkers have a 20% lower risk of stroke (52, 53).

Bottom Line: Coffee may cause mild increases in blood pressure, which usually diminish over time. Coffee drinkers do not have an increased risk of heart disease, but a slightly lower risk of stroke.

12. Coffee May Help You Live Longer

Given that coffee drinkers are less likely to get many diseases, it makes sense that coffee could help you live longer.

There are actually several observational studies showing that coffee drinkers have a lower risk of death.

In two very large studies, drinking coffee was associated with a 20% lower risk of death in men and a 26% lower risk of death in women, over a period of 18-24 years (54).

This effect appears to be particularly strong in type II diabetics. In one study, diabetics who drank coffee had a 30% lower risk of death during a 20 year study period (55).
Bottom Line: Several studies show that coffee drinkers live longer and have a lower risk of premature death.

13. Coffee is The Biggest Source of Antioxidants in The Western Diet

For people who eat a standard Western diet, coffee may actually be the healthiest aspect of the diet.

That’s because coffee contains a massive amount of antioxidants.

In fact, studies show that most people get more antioxidants from coffee than both fruits and vegetables… combined (56, 57, 58).

Coffee is one of the healthiest beverages on the planet. Period.

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The International Diabetes Federation has said that no fewer than 3.9 million Nigerians have been diagnosed with Type 2 diabetes.

The global body, in a statement, as part of activities to mark the World Diabetes on November 14, added that over 11 million Nigerians who have high blood sugar are currently undiagnosed.

The IDF states, “No fewer than 387 million people are currently living with diabetes. It is sad that at least one in every two people who have this condition in developing countries, especially in Africa do not know.”

In view of the recent statistics, a diabetes care specialist, Dr. Afoke Isiavwe, said there was an urgent need to increase awareness about this disease through screening.

According to Isiavwe, who is the Chief Medical Director, Rainbow Specialist Medical Centre, Lagos, early detection will ensure that Nigerians at pre-diabetic stages are picked early and offered the right treatment.

She said, “The IDF atlas reveals that one person dies from diabetes every six seconds around the world. The federation also estimates that over 11 million Nigerians are currently undiagnosed.

“This is why we have decided to provide the opportunity for every Nigerian to come forward for the free screening to help reduce unnecessary death from diabetes, in the country,”

The podiatrist added that on November 14, the World Diabetes Day, the hospital would hold a free diabetes boot camp, focusing on foot care and nutrition in diabetes in Lagos.